NUPACK is a growing software suite for
the analysis and design of nucleic acid systems.
The NUPACK web server currently enables:
- Analysis:
thermodynamic analysis of dilute solutions of interacting nucleic acid strands.
-
Design:
sequence design for an arbitrary number of nucleic acid strands
intended to adopt a target secondary structure at equilibrium, or
to execute a prescribed reaction pathway.
-
Utilities:
evaluation, display, and annotation of equilibrium properties of a complex
of nucleic acid strands.
NUPACK has just released a new multi-state design algorithm and scripting syntax.
Try out the new demos and
please report any bugs to .
NUPACK algorithms are formulated in terms of nucleic acid secondary structure.
In most cases, pseudoknots are excluded from the structural ensemble.
You are welcome to use the NUPACK web server for your research.
Please cite
NUPACK algorithms and the NUPACK web server appropriately.
